Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model마우스 모델에서 SARS-CoV-2 공격에 대한 보호 반응 유도에 대한 최적화된 서열과 SARS-CoV-2의 스파이크 단백질 야생형 DNA 서열의 비교Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 비임상, 진단, [키워드] acid Against Antiviral binding breath CD4 CD8+ cellular immune responses cellular immunity challenge clinical trial contributing to COVID-19 CTL demonstrated DNA DNA vaccine expression full-length spike protein hACE2 humoral humoral and cellular immunity IFN-γ immune immune responses immunogen in vitro induction mice Model mouse Neutralizing antibodies optimization optimizations pGX-9501 platform Protective Protective effects protective response RBD binding response robust SARS-CoV-2 sequence spike Spike protein subsequent T cell T cells the vaccine Transgenic mouse Type virus wild-type wild-type sequence. [DOI] 10.1080/21645515.2021.2016201 PMC 바로가기 [Article Type] Article
Molecular detection of SARS-COV-2 in exhaled breath at the point-of-needArticle Published on 2022-12-012022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Aerosols Analysis Antigen approach approach breath contagious contagiousness detect diagnostics Direct equipment help identify impactor Infection Lab-on-a-chip less limitation molecular Nasopharyngeal swab offer Particle Pathogens patients PCR positive quantification respiratory infections RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2. Spread subject temporal dynamics tested Viral load Viral RNA viral shedding Volume while [DOI] 10.1016/j.bios.2022.114663 PMC 바로가기
Comparison of maternal and neonatal outcomes of COVID-19 before and after SARS-CoV-2 omicron emergence in maternity facilities in Malawi (MATSurvey): data from a national maternal surveillance platformArticle Published on 2022-11-012022-11-16 Journal: The Lancet. Global health [Category] SARS, 변종, [키워드] Abstract adjusted age breath Clinical features COVID-19 death demographic demographic characteristics died enrolment event Fisher foundation health-care less Logistic regression material Maternal Melinda Gate National Neonatal Neonate Odds ratio outcome pandemic Patient platform Pregnancy pregnant pregnant patients reported SARS-CoV-2 SARS-COV-2 infection second wave Stillbirth sub-Saharan Africa Surveillance Symptom symptomatic symptoms of COVID-19 the SARS-CoV-2 translation Wellcome Trust [DOI] 10.1016/S2214-109X(22)00359-X PMC 바로가기
Advanced setup for safe breath sampling and patient monitoring under highly infectious conditions in the clinical environmentArticle Published on 2022-10-262022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Analysis being Biomarker breath caused Compound condition conditions contagious disease transmission Effects examined immediate effect Infection infection risk infectious condition intensive care Observed offer Patient physiological point-of-care profiles protocol provided proximal reduce respiratory infections respiratory rate risk Safe SARS-CoV-2 specific effect subject Transmission Viral load VoC VOCs [DOI] 10.1038/s41598-022-22581-7 PMC 바로가기
Mask assistance to colorimetric sniffers for detection of Covid-19 disease using exhaled breath metabolitesResearch article Published on 2022-10-012022-10-05 Journal: Sensors and Actuators B: Chemical [Category] 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome approach breath Breath analysis calculated change changes in Colorimetric sniffers Comorbidity Complexes component Compound coronavirus correlation COVID-19 detection cured detect diabete diagnosed diagnostic Diagnostic method died disease effective evaluated Face mask globe Gold nanoparticle healthy Human Interaction introduced kidney linear lung management Mask metabolite metabolomics monitoring Non-invasive methods optical Patient porphyrins rapid test kit responses rRT-PCR SARS-CoV-2 severity smoker the disease unique Viral load World Health Organization [DOI] 10.1016/j.snb.2022.132379 [Article Type] Research article
Exhaled breath SARS-CoV-2 shedding patterns across variants of concernArticle Published on 2022-10-012022-11-16 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha Antigen breath Cochran Q test Cohort comparable confidence interval COVID-19 Exhaled Breath Infection infections interquartile range IQR median nasopharyngeal nasopharynx not differ Patient peak peaked performed polymerase chain qPCR Quantitative SARS-CoV-2 SARS-COV-2 infection Test variants variants of concern Viral shedding. Wilcoxon-Mann-Whitney [DOI] 10.1016/j.ijid.2022.07.069 PMC 바로가기
Clinical studies of detecting COVID-19 from exhaled breath with electronic noseArticle Published on 2022-09-262022-11-15 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] Accuracy affecting Analysis breath can be used clinical continuous monitoring coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic detect diagnostic methods exploratory gold standard help hospital limit Local metabolism Non-invasive Numerous pandemic Patient PCR point-of-care test polymerase chain problem reported Research Schools spread of COVID-19 Treatment viral infections virus infection VoC VOCs [DOI] 10.1038/s41598-022-20534-8 PMC 바로가기
Clinical trial and detection of SARS-CoV-2 by a commercial breath analysis test based on Terahertz technologyArticle Published on 2022-09-202022-11-15 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] Algorithm Analysis Asymptomatic Brazil breath clinical Compound correlation COVID-19 diagnosing Diagnostic method evaluate gold standard Health Infection International Local National non-infected noninvasive organic Pandemics Patient Public Rapid required respiratory diseases RT-qPCR SARS-CoV-2 SARS-CoV-2 positivity screening method sensitivity social isolation specificity statistical tested the SARS-CoV-2 threat Trial virus [DOI] 10.1371/journal.pone.0273506 PMC 바로가기
Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease용도 변경 항암 표피 성장 인자 수용체 억제제: 알츠하이머 병에서 신경 보호 효과의 메커니즘Review Published on 2022-09-012022-09-11 Journal: Neural Regen Res [Category] 비임상, [키워드] Alzheimer's disease Alzheimer’s disease animal model autophagy breath caused disease Disease progression downstream signaling pathway downstream signaling pathways drug drug re-positioning Effect effective enhancement epidermal epidermal growth factor epidermal growth factor receptor Evidence examined explained growth factor human epidermal growth factor receptor-2 kinase inhibitors mechanism modulation molecular mechanism neurodegeneration neurodegenerative Neurodegenerative diseases Neuroinflammation neurological manifestation neurological manifestations Numerous oxidative oxidative stress Perspective positioning Prospective clinical trial recent receptor receptor inhibitor Research shown signaling pathways therapeutic approach tyrosine tyrosine kinase inhibitors Tyrosine kinase inhibitors. [DOI] 10.4103/1673-5374.332132 PMC 바로가기 [Article Type] Review
Role of Breath Biopsy in COVID-19Article Published on 2022-09-012022-11-15 Journal: The journal of applied laboratory medicine [Category] 바이오마커, [키워드] affected Analysis approach biochemical Biomarker Biomarkers biopsy breath breath analyzers caused contagious country Coverage COVID-19 COVID-19 diagnosis diagnosis of COVID-19 healthcare mass spectrometry. noninvasive reproducibility Respiratory disease role SARS-CoV-2 sensitivity specificity transmitted VOCs [DOI] 10.1093/jalm/jfac040 PMC 바로가기